For directions for use and additional information click here
Directions for use Apply every night, after facial cleansing using milk and lotion. Specifically active products can possibly be applied as an extra layer under this night cream..
Additional information(1) An elastigenese night cream with nourishing qualities which helps to improve the moisture balance in the skin, partly by the rich extract of papaya. Of great importance in this product is the influence of ‘rejuvenating’ Tinticosyn®, a revolutionary conception of Medex. This natural extract supports the regeneration process strongly, stimulating the production of various proteins in the extracellulary matrix. Papaya Night Cream is especially recommended for dry skin. Combined with Cream Desensible it shows astonishing results for sensitive skin suffering from all kinds of impairments.
Citric Acid Alpha-Hydroxy Acid found in many fruits, especially citrus fruits. It is used in small concentrations as a pH adjuster in cosmetic products. In higher concentrations Citric Acid is used for its peeling properties, combined with its anti-oxidant properties, thereby stimulating the synthesis of new epidermal cells, leaving the skin’s barrier function intact.
Hyaluronic Acid Hyaluronic Acid itself is a substance that is widely found in human connective tissue in the skin. This complex molecule takes care of the moisture balance because of its strong hydrating properties.
Hyaluronic acid is a body’s own polymer, frequently occurring in the skin as one of the so called “glycosaminoglycans”, also called “mucopolysaccharides”, the ground substance of connective tissue. The water binding capacity of hyaluronic acid plays a key role in connective tissue, since it determines its viscosity to a high extend. The carbohydrates from which hyaluronic acid is build are alternating N-Acetylglucosamine and D-Glucuronic acid, building a non-branched polymer together. Hyaluronic acid is a polyanion because of the carboxylate functional group of D-Glucuronic acid. Hyaluronic acid is also an important part of cartilage and estimates highly its elastic properties. Furthermore, hyaluronic acid partly determines the viscosity of synovial fluid in the joints, where it has a lubricating function, enabling the joints to move smoothly.
- Molecular Weight: because hyaluronic acid is a polymer, it has a wide range of different molecular weights from 5000 to 20 Million Dalton, which results in a range of mutually varying properties. Low molecular weight is called for example 1 Million Dalton, since the molecular weight of hyaluronic acid in the human body is 4 to 5 Million Dalton on average, while the molecular weight of hyaluronic acid in synovial fluid is 3 to 4 Million Dalton.
- Signal molecules: in the human body hyaluronic acid is broke down on purpose by enzymes, called Hyaluronidases. These breakdown products are usually oligosaccharides and sometimes function as a signal molecule for fibroblasts, that produce new collagen and elastin. When hyaluronic acid is broke down even more, e.g. in the liver, the final decomposition products are a.o. water and carbon dioxide.
- Application: in cosmetics / skin care as a powerful moisturizer upon/in the skin (the horny layer) and also in cosmetic medicine as a (sub)dermal “filler”, in which case usually a cross-linked version is used. A third application in favour of the skin is cosmetic mesotherapy, where the hyaluronic acid is transferred into the skin, 1 mm down at the dermal-epidermal junction, where it stimulates the fibroblasts’ synthesis, resulting in extra collagen and elastin for the skin.
Tinticosyn, which is prepared from a unique yeast extract, is responsible for the production of new collagen as well as new elastin in the skin. This strengthens the Extracellular Matrix of the skin, thereby minimalizing the visible signs of the ageing process, including fine lines and wrinkles. Furthermore, Tinticosyn supports the stimulation of the skin cells’ metabolism, restoring the energy level of the ageing skin back to the level of a younger skin.
Tinticosyn according to INCI: MANNITOL (AND) CYCLODEXTRIN (AND) YEAST EXTRACT (AND) DISODIUM SUCCINATE)
Ageing skin Our body changes unavoidably when we grow older. All body cells show a similar pattern: they age slowly while time passes. Skin cells are also exposed to other external ageing factors like sunlight, pollution and extreme temperatures. The young skin’s elasticity and firmness is secured by a fine network of dermal fibers: collagen and elastin, which are produced by fibroblasts in the skin’s connective tissue. Unfortunately, these protein fibers are damaged by proteolytic enzymes, which are released by damaging environmental conditions, like sunlight and pollution. The skin’s capacity to resist this process diminishes unremittingly, especially because the metabolism slows down due to ageing, which is caused by a dwindling microcirculation in the skin. It is this microcirculation which is responsible for the supply of sufficient nutrients to the fibroblasts. Tinticosyn helps to reduce the effect of the ageing process, by stimulating the production of Collagen, Elastin and Glycosaminoglycans, all of which are proteins supporting the skin’s firmness, which reduce the visible signs of ageing.